SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--SonoThera™, a biotechnology company dedicated to treating the root cause of human diseases through developing the next generation of genetic medicines, today announced it will present new data at the annual Muscular Dystrophy Association (MDA) Clinical & Scientific Conference, being held March 16-19^th in Dallas, Texas.

The preclinical data highlights the ability of ultrasound-mediated delivery (UMD) to express nonviral genetic constructs in a redosable, durable manner, allowing full-length dystrophin expression in skeletal, cardiac and diaphragm muscles in murine models. SonoThera is developing a proprietary, nonviral, non-invasive approach using ultrasound-mediated delivery, which enables broad, highly targeted biodistribution of diverse genetic medicines without size restriction in a redosable manner, designed to be safe, well-tolerated and cost-effective.

“We are focused on the significant challenges that remain for the treatment of DMD which include the inability to deliver full-length dystrophin, viral vector immunogenicity, failure to improve motor function, inability to redose, safety issues, and of course, the high cost of treatment,” said Kenneth Greenberg, PhD, CEO of SonoThera. “We believe UMD can solve these issues and do so in a nonviral, non-invasive way. We look forward to sharing our latest data at the upcoming MDA conference.”

Oral Presentation Details:

Title: Non-Viral Gene Therapy for DMD Allowing Full-Length Dystrophin Delivery to Skeletal, Cardiac, and Diaphragm Muscles.
Date: Wednesday, March 19, 2025
Time: 11:30am CDT
Location: Cortez CD
Full conference agenda can be found here.

About SonoThera

SonoThera is a biotechnology company dedicated to treating the root cause of human diseases through developing the next generation of genetic medicines. Our nonviral technology is designed to overcome all prevailing limitations of genetic medicine, enabling a pipeline of products which leverages our novel capabilities. Using ultrasound-mediated delivery (UMD), we are developing a proprietary, non-invasive approach which enables broad, highly targeted biodistribution, delivery of diverse genetic payloads without size restriction, in a redosable manner designed to be safe, well-tolerated and cost-effective.

Founded by Drs. Kenneth Greenberg, Michael Davidson, and Steve Feinstein, SonoThera is headquartered in South San Francisco.

Visit us at www.sonothera.com and connect with us on LinkedIn, BlueSky and X/Twitter.